Women's health, 12.5% of the MCQ exam

Gynaecological oncology

Cervical, endometrial, ovarian and vulval cancers, and the cervical screening program. The screening pathway is very testable.

High-yield points

  • Cervical screening: HPV test every 5 years for women and people with a cervix aged 25-74, replacing 2-yearly Pap smears since December 2017.

  • Self-collected vaginal HPV samples are available to everyone eligible since July 2022 and are as accurate as clinician-collected.

  • HPV 16/18 detected: refer directly for colposcopy; other oncogenic HPV types: reflex liquid-based cytology triages the next step.

  • Symptomatic women (post-coital or intermenstrual bleeding) need a diagnostic co-test and examination, not a screening test.

  • Endometrial cancer typically presents with postmenopausal bleeding; risk factors are obesity, unopposed oestrogen, tamoxifen and Lynch syndrome.

  • Ovarian cancer has no effective screening test; persistent bloating, early satiety or pelvic pain warrants CA-125 and transvaginal ultrasound.

  • Vulval itch or lesions that do not settle in older women need biopsy (lichen sclerosus and vulval cancer).

India vs Australia

Where the answer the AMC marks correct differs from what’s usually taught in Indian MBBS.

  • Cervical screening

    India (MBBS)

    Opportunistic Pap smear or VIA, usually from 30.

    Australia (AMC): what the exam expects

    HPV test every 5 years, ages 25-74; self-collection is an option. Cytology only follows a positive HPV test.

  • HPV vaccination

    India (MBBS)

    Cervical cancer is a leading cancer in women; HPV vaccination is being scaled up.

    Australia (AMC): what the exam expects

    School-based program at 12-13 for all genders; aiming to eliminate cervical cancer by 2035.

  • Ovarian cancer

    India (MBBS)

    No screening.

    Australia (AMC): what the exam expects

    Largely the same: no screening; CA-125 and ultrasound are not screening tests in average-risk women.

  • Postmenopausal bleeding

    India (MBBS)

    Often D&C.

    Australia (AMC): what the exam expects

    Transvaginal ultrasound first; endometrial thickness over 4 mm (or ongoing bleeding) needs endometrial sampling.

The Australian context

Australia aims to eliminate cervical cancer as a public health problem by 2035, thanks to the school HPV vaccination program and HPV-based screening. Indian candidates used to opportunistic Pap or VIA screening should learn the Australian HPV-first pathway.